MTOR Monoclonal Antibody (OTI1G4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA805901

Catalog No. 50-168-0885

Description

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

• Antigen: MTOR
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P42345
• Gene Symbols: MTOR
• Immunogen: Human recombit protein fragment corresponding to amino acids 1766-2144 of human MTOR produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI1G4
• Conjugate: Unconjugated
• Gene: MTOR
• Gene Alias: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2475
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid