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MTOR Mouse anti-Human, Clone: OTI1C3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF805908

Catalog No. 50-166-7611


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.
Specifications

Specifications

MTOR
Monoclonal
Unconjugated
MTOR
Lyophilized
MTOR
Human recombit protein fragment corresponding to amino acids 1766-2144 of human MTOR produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
OTI1C3
PBS with 8% trehalose and no preservative; pH 7.3
P42345
FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS
Mouse
IgG2a
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2475
SDS
Documents
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