MTOR Mouse anti-Human, Clone: OTI5B3, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF805914
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOMammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.
|Human recombit protein fragment corresponding to amino acids 1766-2144 of human MTOR produced in E.coli.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS|
|-20° C, Avoid Freeze/Thaw Cycles|
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