MTOR Mouse anti-Human, Clone: OTI5B3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF805914

Catalog No. 50-166-7613

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

• Antigen: MTOR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MTOR
• Gene Alias: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2475
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5B3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P42345
• Gene Symbols: MTOR
• Immunogen: Human recombit protein fragment corresponding to amino acids 1766-2144 of human MTOR produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1