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MUC1 Mouse anti-Human, Clone: 139H2, Abnova™

Mouse monoclonal antibody raised against native human MUC1.

Manufacturer:  Abnova Corporation MAB13365

Catalog No. 89-934-597


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Description

Description

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq]

Specifications

Specifications

MUC1
139H2
Mouse monoclonal antibody raised against native human MUC1.
In 10mM PBS (0.05% BSA, 0.05% sodium azide).
CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM
Mouse
IgG1, kappa
100 ug
Store at 4°C.
Monoclonal
Human
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Unconjugated
Flow Cytometry (0.25-0.5 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
MUC1
Human milk-fat globule membranes (HMFGM).
Protein A/G purification
RUO
Primary
4582
SDS
Documents
Product Certifications
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