Mucin 5AC Mouse anti-Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative), DyLight 405, Clone: 45M1, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP232732V
DescriptionMUC5AC Monoclonal antibody specifically detects MUC5AC in Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative) samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient|
|Protein G purified|
|Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative)|
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|50mM Sodium Borate with 0.05% Sodium Azide|
|gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin|
|Store at 4C in the dark.|
|This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.|
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