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MYC Mouse anti-Human, Clone: 9E10.3, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of human MYC.

Manufacturer:  Abnova Corporation MAB13378

Catalog No. 89-934-641


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Description

Description

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Sequence: AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
Specifications

Specifications

MYC
9E10.3
Mouse monoclonal antibody raised against synthetic peptide of human MYC.
In 10mM PBS.
bHLHe39/c-Myc
Mouse
IgG1, kappa
100 ug
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
This monoclonal antibody shows no cross-reaction with v-myc.
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Unconjugated
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
MYC
A synthetic peptide (conjugated with KLH) corresponding to amino acids 408-439 at C-terminus region of human MYC.
Protein A/G purification
RUO
Primary
4609
Human
SDS
Documents
Product Certifications
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