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MYC tag Mouse anti-Tag, Clone: 1A5A2, Proteintech
SDP

Catalog No. 501736185 Shop All Proteintech Group Inc Products
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50-173-6185 150 μL
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Catalog No. 50-173-6185 Supplier Proteintech Group Inc Supplier No. 600032IG150UL
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Description

Mouse Monoclonal Antibody

The antibody recognizes the Myc-tag EQKLISEEDL fused to either the amino- or carboxy- terminus of targeted proteins.

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Specifications

Antigen MYC tag
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1A5A2
Concentration 0.85 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Alias EQKLISEEDL, Myc tag
Host Species Mouse
Immunogen Peptide
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Tag
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