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Myeloid Specific Antigen Mouse anti-Human, Clone: OTI4H6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526846

Catalog No. PIMA526846


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Description

Description

Interferon-inducible proteins include IFI-202, IFI-203, IFI-204 and D3, which are encoded by six or more structurally related and IFN-inducible mouse genes mapping at the q21-q23 region of chromosome 1. The proteins encoded by these genes have homologous 200 amino acid segments. IFI-202 is a 52 kDa, primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFκB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-gamma in HL60 cells. At least four of the Gene 200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.
Specifications

Specifications

Myeloid Specific Antigen
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P41218
Myeloid cell nuclear differentiation antigen; PYHIN3
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4332
Immunohistochemistry (Paraffin), Western Blot
OTI4H6
Unconjugated
MNDA
Liquid
MNDA
Human recombit protein fragment corresponding to amino acids 37-321 of MNDA produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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