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MYO1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 174991AP

Catalog No. 50-173-1606


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Description

Description

The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding  ft.neck ft. region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein encoded by this gene envelops an actin core bundle that, by comparison, is static in structure.
Specifications

Specifications

MYO1A
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O88329, Q62774, Q9UBC5
BBM I, BBMI, Brush border myosin I, DFNA48, MIHC, MYHL, MYO1A, Myosin I heavy chain, myosin IA
Rabbit
IgG
150 μL
-20°C
Primary
299509, 432516, 4640
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
MYO1A
Liquid
Myo1a
MYO1A Fusion Protein Ag11682
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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