MyoD, Rabbit anti-Human, Biotin, Clone: MYOD1/2075R, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275772B

Catalog No. NB009081

Description

MyoD Monoclonal antibody specifically detects MyoD in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: MyoD
• Clone: MYOD1/2075R
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: MYOD1
• Immunogen: Recombinant full-length human MyoD protein
• Monoclonal or Polyclonal: Monoclonal
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Test Specificity: Recognizes a phospho-protein of 45kDa, identified as MyoD. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD labels the nuclei of myoblasts in developing muscle tissues. MyoD is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

• Applications: Immunohistochemistry,Immunohistochemistry (Paraffin)
• Conjugate: Biotin
• Format: Purified,Conjugated
• Gene Alias: bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
• Host Species: Rabbit
• Isotype: IgG
• Primary or Secondary: Primary
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
• Target Species: Human