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Myogenin Mouse anti-Human, Mouse, Rat, Porcine, Feline, Alexa Fluor™ 750, Clone: MGN185 + F5D, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP234684AF750
SDSDocumentsProduct Certifications Promotions
DescriptionMyogenin Monoclonal specifically detects Myogenin in Human, Mouse, Rat, Porcine, Feline samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
|Alexa Fluor 750|
|50 mM sodium borate with 0.05% sodium azide|
|Human Myogenin recombinant protein (MGN185); Rat Myogenin recombinant fragment containing amino acid 30-224 (F5D) (Uniprot: P15173)|
|Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.|
|Store at 4°C in the dark.|
|Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|MGN185 + F5D|
|Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|BHLHC3, bHLHc3Myogenic factor-4; myogenin, Class C basic helix-loop-helix protein 3, myf-4, MYF4myogenin, Myogenic factor 4, MYOGENIN, myogenin (myogenic factor 4)|
|Protein A or G purified|
|Cancer, Stem Cell Markers, Transcription Factors and Regulators|
|Human, Mouse, Rat, Porcine, Feline|
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