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MYH7 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550240

Catalog No. PA550240


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Description

Description

The antibody detects endogenous levels of total Myosin-7 protein.

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predomitly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
Specifications

Specifications

MYH7
Polyclonal
Unconjugated
MYH7
Liquid
MYH7
Fusion protein corresponding to residues near the C terminal of human myosin, heavy chain 7, cardiac muscle, beta
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P12883
CMH1, MPD1, SPMD, SPMM, CMD1S, MYHCB
Rabbit
IgG
100 μL
-20°C
Primary
4625
Documents
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