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Myotrophin Mouse anti-Human, Clone: 1F3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524520

Catalog No. PIMA524520


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Description

Description

Peptide Sequence: MCDKEFMWAL KNGGLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ

The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3 ft. end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
Specifications

Specifications

Myotrophin
Monoclonal
Unconjugated
MTPN
Liquid
MTPN
MTPN (AAH28093, 1 a.a. ∽ 118 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
1F3
PBS with no preservative; pH 7.4
P58546
MTPN
Mouse
IgG2a, kappa
100 μg
-20° C
Primary
136319
Documents
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