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Alfa Aesar™ N-Methoxycarbonyl-L-tert-leucine, 98%

Manufacturer:  Alfa Aesar™ H3514814

Quantity 25g

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Catalog No. AAH3514814


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Specifications

Description

Applications
The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.

Solubility
Soluble in ethyl acetate and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.
Description & Specifications

Chemical Identifiers

162537-11-3
189.21
N-Moc-L-tert-leucine
C8H15NO4
MFCD07778455
N-Methoxycarbonyl-L-tert-leucine

Specifications

162537-11-3
25g
189.21
N-Moc-L-tert-leucine
98%
107° to 110°C
C8H15NO4
MFCD07778455
N-Methoxycarbonyl-L-tert-leucine

Safety and Handling

SDS & Safety Documents

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

Recommended Storage : 2° to 8°C

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