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N,N-Dimethylsphingosine, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
This item is not returnable. View return policy
119567-63-4
C20H41NO2
327.553
YRXOQXUDKDCXME-QWKHPXNBSA-N
n,n-dms,unii-l9qra71834,nn-dimethyl-d-erythrosphingosine,4-octadecene-1,3-diol, 2-dimethylamino-, s-r*,s*-e,d0os7u,n,n-dimethylsphingosine tlc,e,2r,3s-2-dimethylaminooctadec-4-ene-1,3-diol,e,2r,3s-2-dimethylamino octadec-4-ene-1,3-diol,2r,3s,4e-2-dimethylamino-4-octadecene-1,3-diol,e,2r,3s-2-dimethylamino-octadec-4-ene-1,3-diol
6438166
(E,2R,3S)-2-(dimethylamino)octadec-4-ene-1,3-diol
CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O
This item is not returnable. View return policy
119567-63-4
C20H41NO2
327.553
YRXOQXUDKDCXME-QWKHPXNBSA-N
n,n-dms,unii-l9qra71834,nn-dimethyl-d-erythrosphingosine,4-octadecene-1,3-diol, 2-dimethylamino-, s-r*,s*-e,d0os7u,n,n-dimethylsphingosine tlc,e,2r,3s-2-dimethylaminooctadec-4-ene-1,3-diol,e,2r,3s-2-dimethylamino octadec-4-ene-1,3-diol,2r,3s,4e-2-dimethylamino-4-octadecene-1,3-diol,e,2r,3s-2-dimethylamino-octadec-4-ene-1,3-diol
6438166
(E,2R,3S)-2-(dimethylamino)octadec-4-ene-1,3-diol
CCCCCCCCCCCCCC=CC(C(CO)N(C)C)O

Sphingosine kinase inhibitor

Competitive sphingosine kinase (SphK) inhibitor. Exhibits inhibitory activity in platelets and in cytosolic extracts from U937, Swiss 3T3 and PC12 cells. Selectively inhibits sphingosine phosphorylation; does not inhibit N-acylation, and displays no inhibitory effect on protein kinase C at concentrations that inhibit SphK. Increases the release of IL-1β and MCP-1 in cultured astrocytes; thought to mediate mechanical allodynia via this mechanism.

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Quantity 10mg
Formula Weight 327.55
Percent Purity >98%
Chemical Name or Material N, N-Dimethylsphingosine

Recommended Storage : Store at -20°C