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  7. Nalidixic acid, 99.5%, Thermo Scientific Chemicals

Nalidixic acid, 99.5%, Thermo Scientific Chemicals

Catalog Number ac169900050
Click to view available options
Quantity:
5 g
25 g
100 g
Packaging:
Glass bottle
389-08-2
C12H12N2O3
232.24
MFCD00006884
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
4421
CHEBI:100147
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
389-08-2
C12H12N2O3
232.24
MFCD00006884
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
4421
CHEBI:100147
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O

Description

Nalixidic acid, or nalixidin, CAS # 389-08-2, is a quinolone antibiotic used to inhibit DNA gyrase and prevent cell division.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Nalixidic acid is a synthetic quinolone that is a monocarboxylic acid composed of 1,8-naphthyridine substituted with carboxylic acid, ethyl, and methyl groups

• Nalixidic acid is a DNA gyrase inhibitor that prevents DNA synthesis and subsequent cell divisions

Applications

• Nalixidic acid is primarily effective against gram-negative bacteria

• It may be useful for bacterial resistance studies and laboratory research on drug allergies and cross-reactivity

• Nalixidic acid is suitable for high-performance liquid chromatography (HPLC) and related biochemistry laboratory applications

TRUSTED_SUSTAINABILITY
CAS Min % 99.4
CAS Max % 100.0
Melting Point 225.0°C to 231.0°C
Color White to Yellow
Infrared Spectrum Authentic
Assay Percent Range 99.5%
Packaging Glass bottle
Quantity 5 g
Beilstein 25, V,7, 384
Merck Index 15, 6444
Solubility Information Solubility in water: 0.1g/L (23°C). Other solubilities: soluble in alkali solutions,35mg/mL chloroform- 1.6mg/mL toluene (23°C),1.3mg/mL methanol- 0.9mg/mL ethanol (23°C),0.1mg/mL ether (23°C)
Formula Weight 232.24
Percent Purity 99.5%
Physical Form Powder
Chemical Name or Material Nalidixic acid, 99.5%
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Safety and Handling

Hazard Category GHS Signal Word: Danger
Hazard Statement GHS H Statement
May cause an allergic skin reaction.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statement GHS P Statement
Avoid breathing dust/fume/gas/mist/vapors/spray.
If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
Wear eye protection/face protection.
EINECSNumber 206-864-7
RTECSNumber QN2885000
SDS

RUO – Research Use Only

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