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NAPE PLD Mouse anti-Human, Clone: OTI4B12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525760
DescriptionN-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme which releases the endocannabinoid adamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues. NAPE-PLD has been shown to be expressed by specific populations of neurons in the brain and targeted to axonal processes. Recent studies have suggested that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate the activity of postsynaptic neurons. NAPE-PLD has also been shown to catalyze the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in free-feeding rodents by prolonging latency to feed and postmeal interval.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|N-acyl phosphatidylethanolamine phospholipase D, DKFZp781D1098, FMP30, NAPE-PLD|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit NAPEPLD protein produced in HEK293T cell|
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