NAPSA Mouse anti-Human, Clone: OTI1B5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527023
DescriptionNapsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|KAP, Kdap, NAP1, NAPA, SNAPA, ASP4, TA01/TA02, asp 4, aspartyl protease 4, kidney-derived aspartic protease-like protein, napsin-1, napsin-A, pronapsin A|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 64-244 of NAPSA produced in E.coli|
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