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NAPSA Mouse anti-Human, Clone: OTI3E5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527040

Catalog No. PIMA527040


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Description

Description

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
Specifications

Specifications

NAPSA
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O96009
KAP, Kdap, NAP1, NAPA, SNAPA, ASP4, TA01/TA02, asp 4, aspartyl protease 4, kidney-derived aspartic protease-like protein, napsin-1, napsin-A, pronapsin A
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9476
Immunohistochemistry (Paraffin)
OTI3E5
Unconjugated
NAPSA
Liquid
NAPSA
Human recombit protein fragment corresponding to amino acids 64-244 of NAPSA produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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