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NAPSA Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550329

Catalog No. PA550329


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Description

Description

The antibody detects endogenous levels of total Napsin A protein.

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
Specifications

Specifications

NAPSA
Polyclonal
Unconjugated
NAPSA
Liquid
NAPSA
Fusion protein corresponding to residues near the C terminal of human napsin A aspartic peptidase
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
2.3 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O96009, O09043
KAP, Kdap, NAP1, NAPA, SNAPA
Rabbit
IgG
100 μL
-20°C
Primary
16541, 9476
Documents
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