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Tocris Bioscience™ NBD 556

CD4 mimetic; blocks HIV-1 cell entry

$139.00 - $585.00


Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
581110 View Documents Tocris Bioscience™
5811/10
Each for $139.00
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581150 View Documents Tocris Bioscience™
5811/50
Each for $585.00
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Description

Description

CD4 mimetic (IC50 values are in low micromolar range, dependent on cell type and HIV strain). Recognizes and induces structural changes in HIV-1 envelope protein gp120, analogous to CD4 binding. Inhibits HIV-1 cell entry in CXCR4 and CCR5 expressing cell lines, by blocking virus-cell and cell-cell fusion.
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