Tocris™ NBI 31772

High affinity insulin-like growth factor-I binding protein IGFBP inhibitor

Manufacturer: Tocris™ 5192/10

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Catalog No. 51-921-0

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Disclaimers:

For Research Use Only


    Specifications

    Description NBI 31772
    Molecular Weight 341.27
    Purity >98
    Quantity 10mg
    Product Type NBI 31772

    High affinity insulin-like growth factor-1 binding protein (IGFBP) inhibitor (Ki values are 1 - 24nM for all six human subtypes). Displaces insulin-like growth factor-1 (IGF-1) from the IGF-1:IGFBP complex and suppresses IGF1-induced proliferation of 3T3 fibroblasts. Also increases cardiomyocyte proliferation in vivo.

    • Chemical Name: 1-(3,4-Dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid
    • Formula: C17H11NO7
    • CAS Number: 374620-70-9
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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