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NCAM1 Mouse anti-Human, Clone: OTI2D4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA506223

Catalog No. 50-167-6542


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Description

Description

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa. CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. Polysialic modification results in reduction of CD56-mediated cell adhesion. Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins. CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma. Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors. Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.
Specifications

Specifications

NCAM1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P13591
CD56, MSK39, NCAM
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4684
Western Blot
OTI2D4
Unconjugated
NCAM1
Liquid
NCAM1
Full length human recombit protein of human NCAM1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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