Invitrogen™ NCE2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531221

Catalog No. PIPA531221

Description

Recommended positive controls: NT2D1. Predicted reactivity: Mouse (96%), Rat (83%), Zebrafish (81%), Xenopus laevis (88%), Chicken (92%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.

Specifications

• Antigen: NCE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2F
• Gene Alias: 2510010F15Rik; AI851109; MGC18120; NCE2; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; NEDD8-conjugating enzyme UBE2F; RGD1307608; RING-type E3 NEDD8 transferase UBE2F; UBE2F; Ube2fa; ubiquitin conjugating enzyme E2 F (putative); ubiquitin conjugating enzyme E2F (putative); ubiquitin-conjugating enzyme E2 F; ubiquitin-conjugating enzyme E2F (putative)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140739
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q969M7
• Gene Symbols: UBE2F
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 185 of Human NCE2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov