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ND2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 197041AP

Catalog No. 50-173-2500


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Description

Description

MT-ND2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes. Defects in MT-ND2 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT).
Specifications

Specifications

ND2
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P03891
MT ND2, MTND2, NADH dehydrogenase subunit 2, NADH2, ND2
Rabbit
IgG
150 μL
-20°C
Primary
17717, 4536
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MT-ND2
Liquid
MT-ND2, ND2
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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