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NDST1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548535

Catalog No. PA548535

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Predicted to react with mouse and rat based on sequence homology.

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L- selectin ligands, thereby playing a role in inflammatory response.
Specifications

Specifications

NDST1
Polyclonal
PBS with 0.09% sodium azide
P52848
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Glucosaminyl N-deacetylase/N-sulfotransferase 1, NDST-1, N-heparan sulfate sulfotransferase 1, N-HSST 1, [Heparan sulfate]-glucosamine N-sulfotransferase 1, HSNST 1, Heparan sulfate N-deacetylase 1, 3---, Heparan sulfate N-sulfotransferase 1, 282-, NDST1, HSST, HSST1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3340
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
NDST1
Liquid
NDST1
KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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