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NEFL Mouse anti-Human, Clone: SPM204, Abnova™

Mouse monoclonal antibody raised against native human NEFL.

Manufacturer:  Abnova Corporation MAB13128

Catalog No. 89-934-679


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Description

Description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]

Specifications

Specifications

NEFL
SPM204
Mouse monoclonal antibody raised against native human NEFL.
In 10mM PBS.
CMT1F/CMT2E/FLJ53642/NF-L/NF68/NFL
Mouse
IgG1
100 ug
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Unconjugated
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
NEFL
Native purified NEFL from human brain.
Protein A/G purification
RUO
Primary
4747
SDS
Documents
Product Certifications
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