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NEK9 Mouse anti-Human, Clone: OTI1H1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525650

Catalog No. PIMA525650


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Description

Description

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.
Specifications

Specifications

NEK9
Monoclonal
0.45 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q8TD19
NEK 9; Nek8; nek9; NEK9; Nercc 1 kinase; NERCC; NERCC1; Nercc1 kinase; Never in mitosis A related kinase 9; Never in mitosis A-related kinase 9; NIMA (never in mitosis gene a) related kinase 9; NIMA related kinase 8; NIMA related kinase 9; NIMA related kinase Nek8; NimA related protein kinase 9; NIMA-related kinase 8; NimA-related protein kinase 9; Serine/threonine protein kinase Nek9; Serine/threonine-protein kinase Nek9;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
91754
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1H1
Unconjugated
NEK9
Liquid
NEK9
Full length human recombit protein of NEK9 produced in HEK293 cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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