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Neurogenin 1 Mouse anti-Human, Clone: OTI3F9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524900

Catalog No. PIMA524900


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Description

Description

Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
Specifications

Specifications

Neurogenin 1
Monoclonal
1.0 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q92886
Neurogenin 1, AKA, Math4C, NEUROD3, ngn1, bHLHa6
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4762
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
OTI3F9
Unconjugated
NEUROG1
Liquid
NEUROG1
Full length human recombit protein of NEUROG1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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