Neurogenin 1 Mouse anti-Canine, Human, Clone: OTI8G8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524912
DescriptionBasic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Neurogenin 1, AKA, Math4C, NEUROD3, ngn1, bHLHa6|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Full length human recombit protein of NEUROG1 produced in HEK293T cell|
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