NFIB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 166711AP
DescriptionNF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CTF, HMGIC/NFIB, NF I/B, NF1 B, NFI B, NFI RED, NFIB, NFIB2, NFIB3, Nuclear factor 1 B type, Nuclear factor 1/B, nuclear factor I/B, TGGCA binding protein|
|18028, 29227, 4781|
|NFIB Fusion Protein Ag10165|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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