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NFKBID Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549695

Catalog No. PA549695


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Description

Description

The antibody detects endogenous level of total NFKBID protein.

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I-kappa-BNS, the nuclear I-kappa-B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I-kappa-BNS has been identified as a member of the I-kappa-B family of NF-kappa-B inhibitors, which undergoes induction upon TCR signaling. I-kappa-BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
Specifications

Specifications

NFKBID
Polyclonal
Unconjugated
NFKBID
Liquid
NFKBID
Fusion protein corresponding to a region derived from 1-221 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunohistochemistry (Paraffin), Western Blot
0.9 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q8NI38
IKBNS
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
84807
Documents
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