Invitrogen™ NFU1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596576

Catalog No. PIPA596576

Description

Immunogen sequence: MAATARRGWG AAAVAAGLRR RFCHMLKNPY TIKKQPLHQF VQRPLFPLPA AFYHPVRYMF IQTQDTPNPN SLKFIPGKPV LETRTMDFPT PAAAFRSPLA RQLFRIEGVK SVFFGPDFIT VTKENEELDW NLLKPDIYAT IMDFFASGLP LVTEETPSGE AGSEEDDEVV AMIKELLDTR IRPTVQEDGG DVIYKGFEDG IVQLKLQGSC TSCPSSIITL KNGIQNMLQF; Positive Samples: BT-474, SW480, THP-1, U-937, Mouse liver, Mouse heart, Mouse skeletal muscle, Rat liver, Rat heart; Cellular Location: Cytoplasm, Mitochondrion, cytosol.

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: NFU1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFU1
• Gene Alias: 0610006G17Rik; CGI-33; HIRA-interacting protein 5; HIRIP; Hirip5; histone cell cycle regulation defective interacting protein 5; iron-sulfur cluster scaffold protein; mHIRIP5; MMDS1; Nfu; NFU1; NFU1 iron-sulfur cluster scaffold; NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae); NFU1 iron-sulfur cluster scaffold homolog, mitochondrial; NifU; NIFUC; NifU-like C-terminal domain containing
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27247, 297416, 56748
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9QZ23, Q9UMS0
• Gene Symbols: NFU1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human NFU1 (NP_0010027551).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov