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NFX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 163871AP

Catalog No. 50-173-0912


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Description

Description

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.
Specifications

Specifications

NFX1
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
B1AY10, Q12986
NFX1, NFX2
Rabbit
IgG
150 μL
-20°C
Primary
313166, 4799, 74164
Western Blot
Unconjugated
NFX1
Liquid
Nfx1
NFX1 Fusion Protein Ag9448
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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