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NFYA Polyclonal Antibody, Invitrogen™

Catalog No. PIPA124431
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Quantity:
100 μg
Catalog No. Quantity
PIPA124431 100 μg
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Catalog No. PIPA124431

Supplier: Thermo Scientific PA124431

Description

Rabbit Polyclonal Antibody

PA1-24431 detects Nuclear Trans. Factor Y alpha isoform 1 in Human samples. PA1-24431 has been successfully used in Western Blot procedures. PA1-24431 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human NFYA. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NFYA
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Gene NFYA
Gene Accession No. P23511
Gene Symbols NFYA
Host Species Rabbit
Immunogen Synthetic peptide region of human NFYA.
Purification Method IgG fraction
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4800
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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