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Tocris Bioscience™ NI 57
Potent and selective BRPF bromodomain inhibitor
Supplier: Tocris Bioscience™ 5546/50
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Description
NI 57 is a potent and selective BRPF bromodomain inhibitor (Kd values are 31, 108 and 408 nM, for BRPF1B, 2 and 3, respectively, which exhibits >32-fold selectivity for BRPFs over BRD9 and other non-Class IV bromodomains. NI 57 inhibits RANKL-induced differentiation of primary murine bone marrow cells and human primary monocytes into osteoclasts.Specifications
4-Cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzene-1-sulfonamide | |
50 mg | |
C19H17N3O4S | |
98% |
1883548-89-7 | |
Bromodomain Inhibitors | |
383.42 |
Safety and Handling
Recommended Storage : Store at -20°C
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