Invitrogen™ NIPSNAP3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559997

Catalog No. PIPA559997

Description

Immunogen sequence: VHVLWWNESA DSRAAGRHKS HEDPRVVAAV RESVNYLVSQ QNMLLIP Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.

The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP3A protein is associated with plasma membrane and partially localized in rafts. NIPSNAP proteins have been suggested to be important in vesicular transport.

Specifications

• Antigen: NIPSNAP3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NIPSNAP3A
• Gene Alias: 1700054F22Rik; AI429120; HSPC299; nipsnap homolog 3A; nipsnap homolog 3A (C. elegans); NIPSNAP3A; NipSnap4; Protein NipSnap homolog 3A; protein NipSnap homolog 4; Target for Salmonella secreted protein C; TASSC
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25934
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UFN0
• Gene Symbols: NIPSNAP3A
• Immunogen: Recombinant protein corresponding to Human NIPSNAP3A. Recombinant protein control fragment (Product #RP-104340).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov