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Nitrofurantoin, 98%, Thermo Scientific Chemicals
Description
Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.
Solubility
Soluble in water (<0.01g/100mL at 19°C), dimethyl sulfoxide and methanol.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Store under dry inert gas. It is hygroscopic in nature. Incompatible with oxidizing agents. It is sensitive to light.
Specifications
| Melting Point | ∼265°C (decomposition) |
| Quantity | 25 g |
| Sensitivity | Hygroscopic; Light sensitive |
| Solubility Information | Soluble in water (<0.01g/100 ml at 19°C),dimethyl sulfoxide and methanol. |
| Formula Weight | 238.16 |
| Percent Purity | 98% |
| Chemical Name or Material | Nitrofurantoin |
Safety and Handling
| Hazard Category | H302-H317-H334-H373 |
| Hazard Statement | GHS H Statement H301-H334-H341-H351-H361-H317 Toxic if swallowed. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Suspected of causing genetic defects. Suspected of causing cancer. Suspected of damaging fertility or the unborn child. May cause an allergic skin reaction. |
| Precautionary Statement | P260-P264b-P270-P272-P280g-P285-P301+P312-P302+P352-P304+P341-P314-P330-P333+P313-P342+P311-P363-P501c |
| EINECSNumber | 200-646-5 |
| RTECSNumber | MU2800000 |
| TSCA | Yes |
| Recommended Storage | Ambient temperatures; Store under Nitrogen |
RUO – Research Use Only
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