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NKG2A/NKG2C/NKG2E Rat anti-Mouse, FITC, Clone: 20d5, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen A15416

Catalog No. 50-113-7706


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Description

Description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Specifications

Specifications

NKG2A/NKG2C/NKG2E, NKG2
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide
Liquid
Klrc1, Klrc2, Klrc3
epitope common to the NKG2A, NKG2C and NKG2E isoforms of the CD94/NKG2 heterodimer
Purified
RUO
4° C
Primary
16641, 16642, 58179
Flow Cytometry
20d5
FITC
Klrc2
CD159A, NKG2, NKG2A, C-lectin type II protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-1/B activating NK receptor, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, natural killer cell l, KLRC1, cd159e, cd159c
Rat
IgG2a, kappa
100 μg
Immunology
Antibody
Monoclonal
Mouse
Documents
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