NKX2.2 Mouse anti-Human, Mouse, Rat, Chicken, Alexa Fluor™ 532, Clone: NX2/294, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233058AF532

Catalog No. NP23308A32

Description

NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: NKX2.2
• Classification: Monoclonal
• Conjugate: Alexa Fluor 532
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: NKX2-2
• Immunogen: Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
• Quantity: 0.1 mL
• Gene ID (Entrez): 4821.0
• Target Species: Human, Mouse, Rat, Chicken
• Isotype: IgG2b κ

• Applications: ELISA
• Clone: NX2/294
• Dilution: ELISA
• Gene Alias: Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Primary or Secondary: Primary
• Test Specificity: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
• Content And Storage: Store at 4°C in the dark.