NME3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549708
The antibody detects endogenous level of total NME3 protein.NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
|Full length fusion protein of Human NME3|
|Antigen affinity chromatography|
|ELISA, Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|NME/NM23 nucleoside diphosphate kinase 3, NDPKC, NDPK-C, NM23H3, DR-nm23, NM23-H3, c371H6.2|
|-20° C, Avoid Freeze/Thaw Cycles|
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