NME3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 151361AP
DescriptionNME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|c371H6.2, DR nm23, KIAA0516, NDK 3, NDP kinase 3, NDPK C, NDPKC, NME3|
|4832, 79059, 85269|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|NME3 Fusion Protein Ag7284|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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