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NME7 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550244

Catalog No. PA550244


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Description

Description

The antibody detects endogenous levels of total NME7 protein.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Specifications

Specifications

NME7
Polyclonal
Unconjugated
NME7
Liquid
NME7
Fusion protein corresponding to residues near the C terminal of human NME/NM23 family member 7
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1.2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9Y5B8
NDK7, NDK 7, MN23H7, nm23-H7
Rabbit
IgG
100 μL
-20°C
Primary
29922
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