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NNC 05-2090 hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (Ki values are 1.4, 15, 19 and 41 μM for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α1- and D2-receptors (IC50 values are 266 and 1632 nM respectively).
Specifications
Quantity | 10 mg |
Formula Weight | 451.01 |
Percent Purity | >98% |
Chemical Name or Material | NNC 05-2090 hydrochloride |
Safety and Handling
Recommended Storage : Desiccate at Room Temperature