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Notch3 Rat anti-Human, Clone: NIZ 8G5, Active Motif™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$116.85 - $356.95

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen Notch3
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3187 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61150
10 μg
Each for $116.85
Add to cart
 
50-199-3186 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61149
100 μg
Each for $356.95
Add to cart
 
Description

Description

NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Specifications

Specifications

Monoclonal
Primary
Notch3
Unconjugated
SDS
Product Certifications
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