NR0B1 Mouse anti-Human, Clone: OTI5F5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526709
DescriptionAHC has been mapped to chromosome Xp21 at the same or close to an X-linked locus involved in sex determination, DSS (for dosage-sensitive sex reversal). The gene corresponding to DSS and AHC (designated DAX-1 for DSS-AHC critical region on the X chromosome, gene 1) has been cloned and shown to be deleted in AHC deletion patients and mutated in AHC non-deletion patients. The carboxy terminal 250 amino acids of the DAX-1-encoded protein, DAX-1, exhibits approximately 50% continuous similarity to the ligand-binding domain of the members of the nuclear hormone receptor superfamily while the amino terminal domain contains a putative DNA-binding motif. DAX-1 binds to retinoic acid responsive elements and down regulates retinoic acid receptor-mediated transcriptional activation.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2, DSS-AHC critical region on the X chromosome protein 1, nuclear hormone receptor, nuclear receptor DAX-1, nuclear receptor DAX1, nuclear receptor subfamily 0 group B member 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 161-430 of NR0B1 produced in E.coli|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok