NR1H3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 143511AP150UL

Catalog No. 50-172-9388

Description

The liver X receptors, LXRA and LXRB (NR1H2), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Specifications

• Antigen: NR1H3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NR1H3
• Gene Alias: Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10062, 22259, 58852
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13133, Q62685, Q9Z0Y9
• Gene Symbols: Nr1h3
• Immunogen: NR1H3 Fusion Protein Ag5697
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG