NR3C2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 218541AP
This antibody is a rabbit polyclonal antibody, specifically reacts with the 107 kDa MCR protein.Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor (MR) and that complex ft.s subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain MR. The corresponding gene for the mineralocorticoid receptor is NR3C2.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P08235, P22199, Q8VII8|
|MCR, Mineralocorticoid receptor, MLR, MR, NR3C2|
|110784, 25672, 4306|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|NR3C2 Fusion Protein Ag16410|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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