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NR5A2 Mouse anti-Human, Clone: OTI3H8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526710

Catalog No. PIMA526710


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Description

Description

NR5A2 (nuclear receptor subfamily 5, group A, member 2), also designated B1-binding factor (B1F or B1F2), CYP7A promoter-binding factor (CPF), fetoprotein-alpha 1 (AFP) transcription factor (FTF, FTZ-F1 or FTZ-F1beta) and liver receptor homolog 1 (LRH-1), is a pre-adipocyte-specific nuclear receptor that regulates expression of aromatase in adipose tissue. NR5A2 belongs to the fushi tarazu factor-1 subfamily of orphan nuclear receptors. NR5A2 transcripts are abundant in the human ovary and testis and are predomitly expressed in tissues of endodermal origin. NR5A2 is a positive transcription factor for ABCG5 and ABCG8 and regulates genes involved in sterol and bile acid secretion from liver and intestine. It induces cell proliferation through the concomitant induction of cyclin D1 and E1, an effect that is potentiated by its interaction with beta-catenin.
Specifications

Specifications

NR5A2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O00482
B1F, B1F2, CPF, FTF, FTZ-F1, FTZ-F1beta, LRH-1, LRH1, hB1F-2, CYP7A promoter-binding factor, alpha-1-fetoprotein transcription factor, b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus, fetoprotein-alpha 1 (AFP) transcription factor, hepatocytic transcription factor, live
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2494
Immunohistochemistry (Paraffin), Western Blot
OTI3H8
Unconjugated
NR5A2
Liquid
NR5A2
Human recombit protein fragment corresponding to amino acids 1-303 of NR5A2 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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