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NRL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 173881AP

Catalog No. 50-173-1544


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Description

Description

Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain. Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors. In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter. Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.
Specifications

Specifications

NRL
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P54845, P54846
D14S46E, neural retina leucine zipper, NRL, NRL MAF, RP27
Rabbit
IgG
150 μL
-20°C
Primary
18185, 290221, 4901
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
NRL
Liquid
Nrl
NRL Fusion Protein Ag11277
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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